abstract：BACKGROUND:Patients with congenital absence of the portal vein (CAPV) often suffer from additional medical complications such as hepatic tumors and cardiac malformations. CASE PRESENTATION:Congenital absence of the portal vein (CAPV) is a rare malformation. We present a case of a 16-year-old Chinese girl with CAPV wit...

journal_title：European journal of medical research

authors： Zhang K,Wang Q,Wang H,Ye H,Guo A,Duan W

更新日期：2014-11-26 00:00:00

abstract：BACKGROUND:The expression of heparanase (HPSE) was associated with postoperative metastatic recurrence in patients with hepatocellular carcinoma (HCC). The six E-box binding sites in the core promoter of the HPSE gene suggested that transcription factors of E-box such as upstream stimulatory factor (USF) might regulate...

journal_title：European journal of medical research

authors： Chen B,Chen XP,Wu MS,Cui W,Zhong M

更新日期：2014-08-23 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the association between leisure-time physical activity (LPA) and the risk of metabolic syndrome (MS). METHODS:Prospective cohort studies of the association between LPA and the risk of MS were retrieved from the PubMed and Embase databases up to 12 August 2013. The sta...

journal_title：European journal of medical research

authors： Huang Y,Liu X

更新日期：2014-04-23 00:00:00

abstract：BACKGROUND:Exacerbations of chronic obstructive pulmonary disease (COPD) are sporadic, acute worsening of symptoms. Identifying predictors of exacerbation frequency may facilitate medical interventions that reduce exacerbation frequency and severity. The objective of this study was to determine predictors of exacerbati...

journal_title：European journal of medical research

authors： Yang H,Xiang P,Zhang E,Guo W,Shi Y,Zhang S,Tong Z

更新日期：2014-04-08 00:00:00

abstract：BACKGROUND:To compare the effect of totally thoracoscopic with conventional, open repair of atrial septal defect. METHODS:Forty atrial septal defect cases were divided into two groups by surgical approach: totally thoracoscopic approach (group A, n = 20) and conventional open approach (group B, n = 20). In group A, su...

journal_title：European journal of medical research

authors： Liu X,Wu Y,Zhu J,Lv X,Tang Y,Sun J,Zhang S

更新日期：2014-03-11 00:00:00

abstract：BACKGROUND:Airway inflammation, especially neutrophilic airway inflammation, is a cardinal pathophysiologic feature in chronic obstructive pulmonary disease (COPD) patients. The ideal biomarkers characterizing the inflammation might have important potential clinical applications in disease assessment and therapeutic in...

journal_title：European journal of medical research

authors： Zhu A,Ge D,Zhang J,Teng Y,Yuan C,Huang M,Adcock IM,Barnes PJ,Yao X

更新日期：2014-03-03 00:00:00

abstract：BACKGROUND:Cardiovascular autonomic neuropathy (CAN) is rapidly growing in all populations worldwide. Baroreflex sensitivity (BRS) is easily applied as a diagnostic test to a large number of individuals in the general population. However, no study has reported the normal reference values of BRS for the CAN diagnostic t...

journal_title：European journal of medical research

authors： Tang ZH,Zeng F,Ye K,Yu X,Zhou L

更新日期：2014-02-12 00:00:00

abstract：BACKGROUND:Dopamine agonists (DA) are the first-choice drug for treatment of the early stage of Parkinson's disease (PD) in subjects younger than 70 years. Recently, a number of third generation DA have been marketed, including transdermal patch of rotigotine and extended release oral formulation of ropinirole and pram...

journal_title：European journal of medical research

authors： Pellicano C,Benincasa D,Fanciulli A,Latino P,Giovannelli M,Pontieri FE

更新日期：2013-12-21 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) is a serious clinical syndrome with a high rate of mortality. In this study, the effects of triptolide on lipopolysaccharide (LPS)-induced ALI in rats were investigated. METHODS:Sixty-five male Sprague Dawley rats(approved by ethics committee of the First Affiliated Hospital of Sooch...

journal_title：European journal of medical research

authors： Gao J,Zhan Y,Chen J,Wang L,Yang J

更新日期：2013-12-17 00:00:00

abstract：BACKGROUND:Relatively large calcific tendinitis with persistent symptoms after extended periods of conservative treatment is an indication for operative therapy. Arthroscopy, as a treatment for calcific tendinitis of the hip abductors and calcinosis circumscripta, has been described previously; however, to our knowledg...

journal_title：European journal of medical research

authors： Peng X,Feng Y,Chen G,Yang L

更新日期：2013-11-23 00:00:00

abstract：BACKGROUND:Melasma is a common hypermelanosis of the face. The use of a classical Q-switched ruby laser (QSRL) to treat melasma is discussed controversially and is associated with frequent adverse effects, such as hyper- or hypopigmentation. Recently a fractional-mode (FRx) QSRL was developed to minimize the adverse ef...

journal_title：European journal of medical research

authors： Hilton S,Heise H,Buhren BA,Schrumpf H,Bölke E,Gerber PA

更新日期：2013-11-14 00:00:00

abstract：BACKGROUND:miRNAs are a class of small non-coding RNA molecules that play an important role in the pathogenesis of human diseases through negative regulation of gene expression. Although miRNA-10b (miR-10b) has been implicated in other tumors, its role in non-small cell lung cancer (NSCLC) is still unknown. The aim of ...

journal_title：European journal of medical research

authors： Liu Y,Li M,Zhang G,Pang Z

更新日期：2013-11-12 00:00:00

abstract：BACKGROUND:Prostate cancer (PCa) originating from the prostate base may intrude into the urinary bladder and may be misdiagnosed as bladder cancer. In this retrospective study, we reviewed the clinic data on PCa cases which were initially misdiagnosed as bladder cancer in order to identify diagnostic methods that would...

journal_title：European journal of medical research

authors： Liu R,Xie X,Zhang Z,Xu Y

更新日期：2013-10-03 00:00:00

abstract：BACKGROUND:Sonography has become the imaging technique of choice for guiding intraoperative interventions in abdominal surgery. Due to artefacts from residual air content, however, videothoracoscopic and open intraoperative ultrasound-guided thermoablation of lung malignancies are impossible. Lung flooding is a new met...

journal_title：European journal of medical research

authors： Lesser TG,Schubert H,Bischoff S,Wolfram F

更新日期：2013-07-10 00:00:00

abstract：BACKGROUND:Osteoporosis affects 200 million people worldwide and places an enormous economic burden on society. We aim to identify the feature genes that are related to osteoprotegerin in osteoporosis and to perform function analysis with DNA microarray from human bone marrow. METHODS:We downloaded the gene expression...

journal_title：European journal of medical research

authors： Wu X,Guo S,Shen G,Ma X,Tang C,Xie K,Liu J,Guo W,Yan Y,Luo E

更新日期：2013-06-03 00:00:00

abstract：BACKGROUND:The aim of the study was to test for human papilloma virus (HPV) infection and human telomerase RNA component (hTERC) gene amplification in tissues derived from esophageal cancer, in esophagus displaying atypical hyperplasia and in normal tissue, and to analyze the relationship between them and discuss wheth...

journal_title：European journal of medical research

authors： Wang YF,Wang XS,Gao SG,Chen Q,Yang YT,Xiao ZY,Peng XQ,Hu XF,Wang QY,Feng XS

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The current pilot study compares the impact of an intravenous infusion of Ringer's lactate to an acetate-based solution with regard to acid-base balance. The study design included the variables of the Stewart approach and focused on the effective strong ion difference. Because adverse hemodynamic effects hav...

journal_title：European journal of medical research

authors： Hofmann-Kiefer KF,Chappell D,Kammerer T,Jacob M,Paptistella M,Conzen P,Rehm M

更新日期：2012-07-06 00:00:00

abstract：BACKGROUND:In intestinal epithelium, tyrosine kinase receptor Ephrin B3 (Eph B3) maintains the architecture of the crypt-villus axis by repulsive interaction with its ligand ephrin-B1. While loss of Eph B3 is linked to colorectal cancer initiation, overexpression of Eph B3 in cancer cell lines inhibits growth and induc...

journal_title：European journal of medical research

authors： Schauer MC,Stoecklein NH,Theisen J,Kröpil F,Baldus S,Hoelscher A,Feith M,Bölke E,Matuschek C,Budach W,Knoefel WT

更新日期：2012-05-14 00:00:00

abstract：BACKGROUND:This study is a pre-planned country-specific subanalysis of results in Germany from a multinational multicenter registry to prospectively assess real-world experience with caspofungin administered for treatment of proven or probable invasive aspergillosis (IA). METHODS:Data from patients treated with caspof...

journal_title：European journal of medical research

authors： Egerer G,Reichert D,Pletz MW,Kaskel P,Krobot KJ,Maertens J

更新日期：2012-04-17 00:00:00

abstract：:Unilateral papillitis caused by Treponema pallidum was found in an immunocompetent homosexual patient with severe vision loss who had received previous antibiotics treatment. Syphilis-related ocular manifestation is more common in the early stages of the disease and it can be associated with a central nervous system l...

journal_title：European journal of medical research

authors： Turchetti P,Pacella F,Pacella E,Mirisola C,Uccella I

更新日期：2012-02-14 00:00:00

abstract：BACKGROUND:Burkholderia cepacia strains have been known to possess the capability to cause serious infections especially in neonatal intensive care units (NICUs), and their multi-drug resistances become a severe threat in hospital settings. The aim of this investigation was to evaluate the B. cepacia complex infections...

journal_title：European journal of medical research

authors： Kuzumoto K,Kubota N,Ishii K,Yumoto K,Ogiso Y,Nakamura T,Katsuyama T,Oana K,Kawakami Y

更新日期：2011-12-02 00:00:00

abstract：BACKGROUND:Patients with human immunodeficiency virus (HIV) infection have an increased risk of cardiovascular diseases. Previous publications described pericardial effusion as one of the most common HIV-associated cardiac affiliations. The aim of the current study was to investigate if pericardial effusion still has a...

journal_title：European journal of medical research

authors： Lind A,Reinsch N,Neuhaus K,Esser S,Brockmeyer NH,Potthoff A,Pankuweit S,Erbel R,Maisch B,Neumann T

更新日期：2011-11-10 00:00:00

abstract：:We investigated the hypothesis that religious commitment could help counter general affective distress, accompanying depressive symptoms, in older age. A total of 34 older adults, all catholic believers, completed self-reported questionnaires on the presence of depressive symptoms, religiosity, health, worry, and the ...

journal_title：European journal of medical research

authors： Pokorski M,Warzecha A

更新日期：2011-09-12 00:00:00

abstract：BACKGROUND:Postoperative hyperthyroidism occurs in approximately one third of patients following parathyroidectomy due to primary hyperparathyroidism (PHP), but has only rarely been described in secondary hyperparathyroidism (SHP). The frequency, course, and laboratory markers of postoperative hyperthyroidism in SHP re...

journal_title：European journal of medical research

authors： Rudofsky G,Tsioga M,Reismann P,Leowardi C,Kopf S,Grafe IA,Nawroth PP,Isermann B

更新日期：2011-08-08 00:00:00

abstract：OBJECTIVE:B7-H4, a member of the B7 family of immunoregulatory receptors, may participate in the negative regulation of cell-mediated immunity. Aberrant B7-H4 expression is detected in some tumors and it plays a role in the occurrence and development of tumors. The aim of this study was to elucidate the functional and ...

journal_title：European journal of medical research

authors： Qian Y,Shen L,Xu C,Wu Z,Brockmeyer NH,Altmeyer P,Wu N,Yao HP

更新日期：2011-07-25 00:00:00

abstract：INTRODUCTION:Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. We aimed to assess hepatic mitochondrial function by a non-invasive (13)C-methionine breath test (...

journal_title：European journal of medical research

authors： Banasch M,Ellrichmann M,Tannapfel A,Schmidt WE,Goetze O

更新日期：2011-06-21 00:00:00

abstract：:Echinocandins represent the newest class of antifungal agents. Currently, three echinocandins, anidulafungin, caspofungin and micafungin are licensed for clinical use in various indications. They act as inhibitors of β-(1,3)-glucan synthesis in the fungal cell wall and have a favorable pharmacological profile. They ha...

journal_title：European journal of medical research

authors： Kofla G,Ruhnke M

更新日期：2011-04-28 00:00:00

abstract：BACKGROUND:Ceftriaxone is commonly used as an alternative antibiotic drug in treating syphilis but clinical data on its efficacy are limited. OBJECTIVE:To evaluate the response of HIV-infected patients with active syphilis to treatment with penicillin or ceftriaxone. - METHODS:A retrospective study involving 24 conse...

journal_title：European journal of medical research

authors： Spornraft-Ragaller P,Abraham S,Lueck C,Meurer M

更新日期：2011-02-24 00:00:00

abstract：:Antibiotic-resistant organisms causing both hospital- and community-acquired complicated skin and soft-tissue infections (cSSTI) are increasingly reported. A substantial medical and economical burden associated with MRSA colonisation or infection has been documented. The number of currently available appropriate antim...

journal_title：European journal of medical research

authors： Eckmann C,Dryden M

更新日期：2010-11-30 00:00:00

abstract：BACKGROUND:Processes of restenosis, following arterial injury, are complex involving different cell types producing various cytokines and enzymes. Among those enzymes, smooth muscle cell-derived matrix metalloproteinases (MMPs) are thought to take part in cell migration, degrading of extracellular matrix, and neointima...

journal_title：European journal of medical research

authors： Preusch MR,Vanakaris A,Bea F,Ieronimakis N,Shimizu T,Konstandin M,Morris-Rosenfeld S,Albrecht C,Kranzhöfer A,Katus HA,Blessing E,Kranzhöfer R

更新日期：2010-11-25 00:00:00

abstract：:Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the product of alternative RNA splicing of db gene. According to its structural differences, the receptor's isoforms are divided into three classes: long, short, and secretory isoforms. A long, fully ...

journal_title：European journal of medical research

authors： Gorska E,Popko K,Stelmaszczyk-Emmel A,Ciepiela O,Kucharska A,Wasik M

更新日期：2010-11-04 00:00:00

abstract：:A fifty-year-old female presented with a one month history of progressive dyspnea, productive cough, pain of elbows and knees, and 40°C fever despite antibiotic treatment. She has been diagnosed of bronchial asthma over 25 years before admission and oral and depot glucocorticosteroids as a long-term therapy was applie...

journal_title：European journal of medical research

authors： Mroz RM,Korniluk M,Swidzinska E,Chyczewska E

更新日期：2010-11-04 00:00:00

abstract：BACKGROUND:Serotonin (5-HT) and its receptors are present in central, the brain stem, and peripheral, the carotid body, tissues controlling the ventilatory responses to hypoxia. The exact action of serotonin and its nature are, however, unsettled. We hypothesized that the discrepant results on the ventilatory action of...

journal_title：European journal of medical research

authors： Pozdzik M,Zajac D,Zasada I,Czarnocki Z,Matysiak Z,Mazzatenta A,Pokorski M

更新日期：2010-11-04 00:00:00

abstract：:Nocturnal cardiac arrhythmias (NCA) were analyzed in patients with sleep apnea/hypopnea syndrome (SAHS) and controls. Occurrence and severity of NCA were compared in 33 SAHS patients and 16 control subjects, matched for cardiovascular risk factors. Continuous overnight polysomnography provided ECG, respiratory and sle...

journal_title：European journal of medical research

authors： Szaboova E,Tomori Z,Szabo P,Gresova S,Donic V

更新日期：2010-11-04 00:00:00

abstract：OBJECTIVE:replication of HIV-1 after cell entry is essentially dependent on the reverse transcriptase (RT). Antiretroviral drugs impairing the function of the RT currently aim at the polymerase subunit. One reason for failure of antiretroviral treatment is the evolvement of resistance-associated mutations in the viral ...

journal_title：European journal of medical research

authors： Michels I,Staszewski S,Gürtler L,Nisius G,Müller A,Locher L,Doerr HW,Stürmer M

更新日期：2010-10-25 00:00:00

abstract：OBJECTIVE:given sparse research on the issue, this study sought to shed light upon the interactions of alexithymia, emotion processing, and social anxiety in adults with attention-deficit hyperactivity disorder (ADHD). SUBJECTS AND METHODS:73 German adults with ADHD according to DSM-IV diagnostic criteria participated...

journal_title：European journal of medical research

authors： Edel MA,Rudel A,Hubert C,Scheele D,Brüne M,Juckel G,Assion HJ

更新日期：2010-09-24 00:00:00

abstract：BACKGROUND:Systemic treatment of head and neck squamous cell carcinoma (HNSCC) includes a variety of antineoplastic drugs. However, drug-resistance interferes with the effectiveness of chemotherapy. Preclinical testing models are needed in order to develop approaches to overcome chemoresistance. - METHODS:Ten human ce...

journal_title：European journal of medical research

authors： Schuler PJ,Trellakis S,Greve J,Bas M,Bergmann C,Bölke E,Lehnerdt G,Mattheis S,Albers AE,Brandau S,Lang S,Whiteside TL,Bier H,Hoffmann TK

更新日期：2010-08-20 00:00:00

abstract：BACKGROUND:Renal impairment is a common complication of multiple myeloma occurring in up to 50 % of patients at some stage in their disease. Due to occurrence of cast nephropathies we hypothesized circulatory dysregulation (vasoconstriction) in the kidneys with measurable elevation of the resistance index among these p...

journal_title：European journal of medical research

authors： Schiemann U,Kaiser HC,Götzberger M,Schmidmaier R,Bantle F,Straka C

更新日期：2010-05-18 00:00:00

abstract：:The purpose of this report is to document a case of unsuspected ameloblastoma involving the right man dibular subpontic region in a 38-year-old Cambodian female patient. This lesion was purportedly preceded by multiple radiolucencies which were diagnosed as radicular cysts and treated a few times in the past years by ...

journal_title：European journal of medical research

authors： Siar CH,Nakano K,Chelvanayagam PI,Ng KH,Nagatsuka H,Kawakami T

更新日期：2010-03-30 00:00:00

abstract：:Plexiform neurofibroma (PN) is a rare benign tumor and a special subtype of neurofibromatosis type 1 (NF1). Though the incidence is low, giant PN of the craniomaxillofacial region could result in severe hemifacial hypertrophy which is known as a typical manifestation of NF1 in young children. Here, we retrospectively ...

journal_title：European journal of medical research

authors： Feng Y,Yang ZG,Chen T,Wang Q,Deng W

更新日期：2010-02-26 00:00:00